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Table 2 Relative levels of MLL2 protein in colonic cell lines

From: Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon

Cell lines

Nuclear MLL2

Cytoplasmic MLL2

 

75 kD

290 kD

75 kD

290 kD

 

(Cleaved)

(Uncleaved)

(Cleaved)

(Uncleaved)

HT29

+

-

-

-

DLD-1

++

-

-

-

Ls174T

++

-

+

-

Lovo

+

-

++

-

Colo205

-

+ + ++

+

+ +

SW480

-

+ + ++

+

+ +

  1. Distribution of cleaved and uncleaved MLL2 protein in nuclear and cytoplasmic fractions of colon carcinoma cell lines
  2. Staining intensity - Negative; + Weak; +++ Moderate, ++++ Intense