Phosphorylation level of p38-MAPK and Akt in H-520 cells after irradiation and ES treatment. A) ES combined with 4Gy irradiation significantly inhibits p38-MAPK phosphorylation. B) Decreased p-Akt in H-520 cells caused by ES treatment. Protein extracts of cells treated with 200 μg/mL ES, 4Gy irradiation, and in combination (ES+4Gy) at 24 h following irradiation. One representative of three independent experiments was shown.