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Figure 1 | Cancer Cell International

Figure 1

From: Effects of myenteric denervation on extracellular matrix fibers and mast cell distribution in normal stomach and gastric lesions

Figure 1

Histological analysis of rat stomachs. A, B, E and F) Pyloric gastric glands (g) surrounded by stroma with collagen fibers (s) observed in the mucosa layer of the groups I and II. Epithelium (ep). Gastric pits (f). Muscularis mucosa (m). C, D, G and H) Pyloric gastric glands (g) constituted by tumoral cells occupied the largest area of the gastric mucosa of the groups III and IV. An accumulation of PMN (arrows) was observed within the glands. Hematoxylin-Eosin (A-D); Picrosirius-Hematoxylin (E-H). Bars: 20 μm. I-L) Tissue compartments (epithelium, stroma, others) volumes of the gastric pyloric mucosa. Values are expressed as mean ± SEM of percentage of relative volume. Groups without lesions (I and II) presented a high relative volume of epithelium (p < 0.05) compared to groups with lesions (III and IV). The presence of adenocarcinoma in the groups III and IV resulted in a significant increase (p < 0.05) of stroma compared to groups I and II.

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