Percent PI-positive MoCR cells. The percent of PI-positive (apoptotic) cells after 24 and 120 hours was assessed using FACs at the same time as CFSE analysis. Although the concentrations of CGP-421112A had their most significant effects at different times and under different background conditions, in general, CGP42112A treatment increased apoptosis. Significant P values are shown with an * and solid line, while those of interest with P values between 0.1 and 0.05 are indicated with a dotted line and no *. Data are presented as mean ± S.E.M.