Figure 2

Effect of doxorubicin on 3D HT1080 cell migration speed. Cells cultured during 48 h within 3D matrix or on 2D plastic were incubated with doxorubicin at 0, 2.5, 5 and 7.5 nM for 24 h and were tracked by time-lapse videomicroscopy during the last 12 h of drug incubation. The migration speed was displayed as a box plots (bottom of box, 25th percentile; and top of box, 75th percentile) and middle line indicates the median (15 cells per sample). *** p < 0.001 significant difference between control and doxorubicin treatment.