Figure 5
From: 3D collagen type I matrix inhibits the antimigratory effect of doxorubicin
Effect of doxorubicin on β1 integrin expression in 3D HT1080 cells. Cells cultured during 48 h within 3D type I collagen matrix or on 2D substrata were incubated with doxorubicin 0 and 5 nM for 24 h. Then, they were stained with total-β1 integrin monoclonal antibody and analyzed by flow cytometry. Data shown are representative of three independent experiments.