Figure 6

Caspase 3 gene expression. Gel electrophoresis of GAPDH amplicons is displayed as control on the left side of figure. (CON = Control, DOC = Doxycycline, CIS = Cisplatin, CD = Cisplatin and Doxycycline, OXA = Oxaliplatin, OD = Oxaliplatin and Doxycycline). The right side of figure displays gel electrophoresis of caspase 3. (NC = Negative control, Con = CON = Positive control, Dox = DOX = Doxycycline, C(CIS)1; C4; C24 = Cisplatin treatment for 1, 4 and 24 hours respectively, cd(CD)1; cd4; cd24 = Cisplatin and Doxycycline treatment for 1, 4 and 24 hours respectively, O(OXA)1; O4; O24 = Oxaliplatin treatment for 1, 4 and 24 hours respectively, od(OD)1; od4; 0d24 = Oxaliplatin and Doxycycline treatment for 1, 4 and 24 hours respectively). Data are depicted as means of six experiments ± standard deviation. (* - Denotes statistically significant difference in the activity).