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Figure 3 | Cancer Cell International

Figure 3

From: A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy

Figure 3

dNSurR9-C84A upregulates the activity of caspase-9 and caspase-3 in cancer cells. (A, B) 3D cultures of DU145 and HeLa cells were treated with dNSurR9-C84A, R9-GST and PBS, and the activities of caspase-9 (A) and caspase-3 (B) were measured 6, 12 and 18 h post-treatment. A statistically significant difference in caspase activity between cells treated with dNSurR9-C84A and R9-GST is denoted as "*". *p < 0.05.

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