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Figure 4 | Cancer Cell International

Figure 4

From: Promotion of tumor development in prostate cancer by progerin

Figure 4

Ectopically expressed progerin failed to induce cellular senescence in the cancer cells. (A) The growth curve of PC-3 cells transfected with lamin A expression constructs or vector control was performed with a MTS assay. The bars represent the mean ± SE (n = 4). (B) SA-beta-Gal staining of PC-3 cells transfected with different lamin A expression constructs or vector control. Photomicrographs were taken at 200 × magnification. Percentages of SA-beta-Gal positive staining were presented below. *P < 0.01, compared with pEGFP vector transfected group.

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