Figure 7From: Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumoursDz13 downregulates target c-Jun levels in ectopic osteosarcoma, prostate and breast tumours. Ectopic osteosarcoma (G292), prostate (PC3) and breast (MDA-MB231) tumour sections were evaluated by immunohistochemistry for c-Jun and c-Fos (off-target control). c-Jun and c-Fos (inserts)-immunostained tumour sections are shown. Representative images are shown. Negative control sections (no primary antibody) ruled out non-specific staining. Scale bar = 25 μm, n = 5.Back to article page