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Figure 9 | Cancer Cell International

Figure 9

From: Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres

Figure 9

Effect of Chalcone-imidazolone conjugates on size and distribution of TRF2 foci in metaphase spreads. MCF-7 cells were synchronized with nocodazole (40 ng/ml) for 6 h time period followed by compound treatment (TMAC, CA-4, 6 and 8) at 30 μM final concentration for 24 h time period. This is followed by colchicine treatment(100 μg/m l) for 5 h and staining procedure was done with TRF2 antibody. Control represents untreated cells.

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