Figure 6From: Antiangiogenic properties of Koetjapic acid, a natural triterpene isolated from Sandoricum koetjaoe MerrEffects of KA on neovascularization in CAM assay. Effect of KA on neovascularization in chorioallantoic membrane of chick embryo. The embryos were treated for 24 h with (A) 1% ethanol as a negative control, (B) 50 μg/ml and (C) 100 μg/ml. The pictures were captured under dissecting microscope. Arrows indicate the place of agarose discs application. KA inhibited the neovascularisation in a dose-dependent manner by 41.8 ± 7.2% and 64.9 ± 8.7% at 50 and 100 μg respectively. Data presented in mean ± SD.Back to article page