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Figure 4 | Cancer Cell International

Figure 4

From: Inverse baseline expression pattern of the NEP/neuropeptides and NFκB/proteasome pathways in androgen-dependent and androgen-independent prostate cancer cells

Figure 4

NFκB activation in PC cell lines. (A) Nuclear and cytoplasmic NFκB levels in PC-3 (left) and LnCaP cells (middle). Right: Nuclear extracts of PC-3 cells at baseline and following bortezomib incubation (1 μM for 60 min). (B) NFκB EMSA. Lane 1: negative control; Lane 2: PC-3 cells; Lane 3: LnCaP cells; Lane 4: HeLa cells (6 hrs post-infection). (C) Total cellular IκBα levels in PC-3 (left) and LnCaP cells (right). (D) Total cellular IκBα levels in PC-3 cells following serial incubations with bortezomib 1 μM.

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