A miRNA expression signature that separates between normal and malignant prostate tissues

Table 2 Differentially expressed miRNAs

miRNA	+/-	p-value	Reported no. of times	Adjusted p-value
MIR126*	-	7.68e-07	11	4.50e-04
MIR34A*	-	1.19e-06	13	6.09e-04
MIR622	+	1.52e-06	9	3.88e-04
MIR195	-	3.06e-06	7	8.55e-04
MIR26A	-	4.05e-06	6	4.50e-04
MIR30D	+	4.35e-06	9	4.50e-04
MIR29A*	-	4.48e-06	4	6.09e-04
MIR425*	+	5.65e-06	6	4.50e-04
MIR342-3P	+	6.11e-06	4	6.09e-04
MIR345	-	1.07e-05	2	1.77e-03
MIR24	-	1.08e-05	3	6.09e-04
MIR484	-	1.12e-05	2	1.16e-03
MIR497	+	1.13e-05	4	6.09e-04
MIR30E	+	1.22e-05	3	6.09e-04
MIR93	+	1.29e-05	3	1.64e-03
MIR221*	-	1.37e-05	1	1.64e-03
MIR774	+	1.44e-05	2	1.64e-04
MIR152	-	2.34e-05	0	1.37e-03
MIR27B	-	2.47e-05	4	8.62e-04
MIR101*	+	3.34e-05	2	4.69e-04
MIR145*	-	3.51e-05	1	4.69e-04
MIR143	-	4.65e-05	1	1.40e-03
MIR100	-	5.12e-05	1	6.09e-04
MIR519B-3P	+	5.12e-05	2	1.40e-03
MIR200C*	+	6.66e-05	1	3.88e-04
MIR501-5P	+	6.80e-05	0	1.12e-03
MIR200C	+	6.84e-05	2	3.88e-04
MIR30A	+	6.84e-05	0	1.64e-03
MIR191	+	7.85e-05	1	6.09e-04
MIR30B	-	9.43e-05	1	2.06e-03

MicroRNAs differentially expressed between normal and malignant tissue samples of the prostate with p < 0.0001. The nine miRNAs in bold text were also significant at the 0.00001 level. The signs +/- indicate if the miRNAs were up- or down-regulated in the malignant tissue compared to the adjacent normal prostate tissue. The reported number of times stands for the number of repetitions in which the miRNA was reported as differentially expressed in the 15-fold cross-validation test.

ISSN: 1475-2867