Treatment/Assay | AO/EB (%) | DiOC6(3)High/Low (%) |
---|---|---|
Untreated | < 1 ± 0 | > 99 ± 0 |
VK3 (1 μM) | 1 ± 1 | 98 ± 1 |
VC (100 μM) | 1 ± 0 | 99 ± 1 |
VK3 (1 μM) + VC (100 μM) | 1 ± 1 | 98 ± 1 |
VK3 (2 μM) | 1 ± 1 | 98 ± 1 |
VC (200 μM) | 1 ± 1 | 98 ± 2 |
VK3 (2 μM) + VC (200 μM) | 2 ± 1 | 97 ± 1 |
VK3 (3 μM) | 5 ± 1a | 96 ± 1 |
VC (300 μM) | 4 ± 1a | 97 ± 1 |
VK3 (3 μM) + VC (300 μM) | 2 ± 1a | 97 ± 2 |
VK3 (4 μM) | 11 ± 1a | 87 ± 3a |
VC (400 μM) | < 1 ± 0c | > 99 ± 0c |
VK3 (4 μM) + VC (400 μM) | 8 ± 1a,b | 92 ± 2a,b,c |
VK3 (5 μM) | 22 ± 1a | 73 ± 2a |
VC (500 μM) | 2 ± 1c | 97 ± 1c |
VK3 (5 μM) + VC (500 μM) | 10 ± 2a,b,c | 88 ± 2a,c |
VC (5000 μM) | 3 ± 1 | 97 ± 2b,c |
VK3 (5 μM) + VC (5000 μM) | 48 ± 2a,b,c | 68 ± 2a,b,c |
VK3 (10 μM) | 35 ± 3a | 60 ± 2a |
VC (10000 μM) | 26 ± 2a | 75 ± 3a,c |
VK3 (10 μM) + VC (10000 μM) | 58 ± 3a,b,c | 63 ± 3a,b |