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Table 2 Expression of Epithelial and Mesenchymal Genes

From: Murine mammary tumor cells with a claudin-low genotype

Gene

4T1

RJ345

RJ348

RM11A

E-cadherin

154 ± 28.2

75.0 ± 19.8

0.87 ± 0.15a

1.01 ± 0.06a

Twist1

0.29 ± 0.05

0.13 ± 0.02

0.67 ± 0.06

0.65 ± 0.23

Twist2

0.02 ± 0.01

0.13 ± 0.04

0.90 ± 0.15a, b

0.91 ± 0.06a, b

Zeb1

0.02 ± 0.01

0.12 ± 0.04

0.89 ± 0.22a, b

1.50 ± 0.16a, b

Zeb2

0.31 ± 0.09

0.02 ± 0.01

0.95 ± 0.04a, b

1.08 ± 0.18a, b

  1. Data is expressed relative to HPRT. Values are displayed as mean ± SEM; n = 3
  2. aSignificantly different (p < 0.05) than 4T1 cells
  3. bSignificantly different (p < 0.05) than RJ345 cells.