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Figure 5 | Cancer Cell International

Figure 5

From: The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells

Figure 5

Evaluating the effect of M344, cisplatin and their combination on the formation of γH2A.X foci. A) Phase contrast images of A2780s cells following 24 hrs of treatment with 5.0 μM M344 alone or in combination with 2 μg/ml cisplatin. B) A2780s cells subjected to combination platinum and M344 24 hr treatment demonstrates increased levels γH2A.X foci detected by immunoflourescence. Repeat of the experiment showed similar findings.

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Cancer Cell International

ISSN: 1475-2867

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