Table 1 IC50 values for ATRA, 4-HPR, and derivatives on various tumor cell lines
From: In vitro activities of novel 4-HPR derivatives on a panel of rhabdoid and other tumor cell lines
|  | IC50 (μM) | |||||||
|---|---|---|---|---|---|---|---|---|
Tumor type Cell lines | Rhabdoid | Glioma | Breast | |||||
| Â | MON | G401 | A204 | SF268 | U87 | U251 | MCF7 | MDAMB231 |
ATRA | > 50 | > 50 | > 50 | > 50 | > 50 | > 50 | > 50 | > 50 |
4-HPR | 2.2 | 0.1 | 2.0 | 6.9 | 5.0 | 1.4 | 2.2 | 0.4 |
5h | 3.6 | 0.3 | 1.7 | 18.9 | 16.3 | 5.8 | 6.3 | N/A* |
5j | 1.2 | 3.0 | 8.2 | 12.0 | 13.7 | 9.1 | 11.8 | 23 |
11a | 1.9 | 0.2 | 4.4 | 10.4 | 5.0 | 2.4 | 8.3 | 2.3 |
11c | 5.2 | 0.3 | 5.6 | 15.7 | 9.3 | 5.9 | 12.1 | 5.3 |
11d | 1.3 | 3.2 | 7.5 | 3.8 | 9.4 | 7.8 | 8.2 | 12.0 |