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Table 1 Hepatic MDA, GSH levels, GR, GPx and SOD activities in different experimental groups

From: The chemopreventive effect of Ginkgo biloba and Silybum marianum extracts on hepatocarcinogenesis in rats

Groups

MDA

(nmol MDA/g tissue)

GSH

(mg/g tissue)

GR

(nmol NADPH reacted/min/mg protein)

GPx

(nmol NADPH reacted/min/mg protein)

SOD

(nmol NADPH reacted/min/mg protein)

Control

11.65 ± 1.10

6.86 ± 1.21

85.94 ± 5.74

102.26 ± 8.43

49.34 ± 3.08

NDEA

22.97 ± 2.79 a

0.43 ± 0.10 a

51.94 ± 2.88 a

18.34 ± 3.49 a

5.28 ± 0.82 a

Pre S.m

13.89 ± 1.89 b

3.38 ± 0.16 b

72.44 ± 3.91 b

25.26 ± 2.76 b

37.04 ± 4.76 b

Pre G.b

14.42 ± 1.56 b

4.54 ± 1.00 b

77.27 ± 13.15 b

36.63 ± 4.10 b

32.28 ± 3.23 b

Post S.m

16.74 ± 2.90 b,c

2.36 ± 0.45 b,c

62.51 ± 5.50 b,c

20.00 ± 1.67 c

17.39 ± 2.40 b,c

Post G.b

17.53 ± 3.32 b,d

3.64 ± 0.57 b,d

61.47 ± 6.42 b,d

29.84 ± 2.92 b,d

20.92 ± 1.77 b,d

  1. Results are given as mean ± S.D. for 6 rats. Pre S.m= Pretreated silymarin, Pre G.b= Pretreated EGb, Post S.m= Posttreated silymarin, Post G.b= Posttreated EGb. a: significantly different from control group at p ≤ 0.05. b: significantly different from NDEA group at p ≤ 0.05. c: significantly different from Pre S.m group at p ≤ 0.05. d: significantly different from Pre G.b group at p ≤ 0.05.