Skip to main content

Table 2 Comparison of EC50 mean values between mutated and not-mutated cell lines.

From: Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression

  

Cell lines without mutations

Cell lines with mutations

  

A

B

C

D

  

Lower

IK EGR-1

n = 6

Higher

IK EGR-1

n = 6

Total

n = 12

Total

n = 6

  

Xa = 22.33

Xa = 48.33

Xa = 35.33

Xa = 54.66

Vincristine

Cb

0.069

0.664

0.339

0.098

 

Ac

27.31

21.21

24.27

38.58

Cisplatin

C

0.427

1.960

1.124

1.784

 

A

15.73

16.83

16.3

4.433

Camptothecin

C

0.472

1.914

1.127

0.025

 

A

2.783

2.992

2.887

1.881

Mitomycin C

C

0.089

0.09

0.075

0.002

 

A

3.218

0.413

1.82

1.715

Etoposide

C

0.819

1.904

1.312

9.410

 

A

50.16

50.66

50.41

85.50

Doxorubicin

C

0.021

0.035

0.027

0.028

 

A

0.758

4.180

2.47

4.820

  1. EC50 values were compared between column A and B, and between column C and D.
  2. Statistically different EC50 values are in bold (see inside text).
  3. Xa = IK EGR-1 mean value
  4. b = clonogenic assay, c = acute cytotoxicity assay