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Figure 2 | Cancer Cell International

Figure 2

From: Molecular network profiling of U373MG human glioblastoma cells following induction of apoptosis by novel marine-derived anti-cancer 1,2,3,4-tetrahydroisoquinoline alkaloids

Figure 2

Induction of apoptosis of U373MG cells by exposure to the anti-cancer chemical compounds. U373MG cells were exposed for 72 hours to the chemical compounds individually at the concentration of IC50. The panels (a-d) represent phase contrast photographs of (a) the vehicle (DMSO), or (b) ET-770, the compound 1a, (c) ET-770 derivative, the compound 3, and (d) renieramycin M (RM), the compound 2a. The round-shaped cells with remarkable shrinkage indicate the cells with ongoing apoptosis.

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