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Figure 5 | Cancer Cell International

Figure 5

From: Molecular network profiling of U373MG human glioblastoma cells following induction of apoptosis by novel marine-derived anti-cancer 1,2,3,4-tetrahydroisoquinoline alkaloids

Figure 5

qPCR of PTK2, AKT3, GSK3B, and CDC25A mRNAs in U373MG cells following exposure to the anti-cancer chemical compounds. The panels (a-d) indicate quantitative RT-PCR (qPCR) analysis of (a) PTK2, (b) AKT3, (c) GSK3B, and (d) CDC25A mRNA expression standardized against the levels of G3PDH in U373MG cells exposed for 4 hours or 24 hours to DMSO (D1) or ET-770 derivative, the compound 3 (M1), or for 24 hours to DMSO (D2) or ET-770, the compound 1a (E2), individually at the concentration of IC50.

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