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Figure 8 | Cancer Cell International

Figure 8

From: Molecular network profiling of U373MG human glioblastoma cells following induction of apoptosis by novel marine-derived anti-cancer 1,2,3,4-tetrahydroisoquinoline alkaloids

Figure 8

Molecular network of downregulated genes in U373MG cells following exposure to renieramycin M, the compound 2a. Entrez Gene IDs of 274 downregulated genes in U373MG cells following a 24 hour-exposure to the compound 2a were imported into IPA. The molecular networks closely related to the set of imported genes were identified. The molecular network defined by “cellular movement, cell morphology, cell-to-cell signaling and interaction” identified as the third-rank downregulated network (Table 3) is shown, where downregulated genes are colored by green.

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Cancer Cell International

ISSN: 1475-2867

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