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Figure 4 | Cancer Cell International

Figure 4

From: ZIP8 expression in human proximal tubule cells, human urothelial cells transformed by Cd+2 and As+3 and in specimens of normal human urothelium and urothelial cancer

Figure 4

Immunoperoxidase staining of ZIP8 in low grade urothelial carcinoma. A. Weak staining of ZIP8 (+) in low grade urothelial carcinoma. Asterisks (*) indicate stromal tissue which is negative for ZIP8. B. low grade urothelial carcinoma of bladder showing weak focal staining of ZIP8 (+). There are areas of the tumor that show negative staining for ZIP8 (−). Asterisks (*) indicate stromal tissue which is negative for ZIP8. C. Low grade urothelial carcinoma from renal pelvis with moderate staining of ZIP8 (+). The tumor stroma is negative for ZIP8 (*). D. Moderate staining of ZIP8 (+) in low grade urothelial carcinoma. Asterisks (*) indicate stromal tissue which is negative for ZIP8. E. Higher magnification of D showing paranuclear staining of ZIP8 (+). Asterisks (*) indicate stromal tissue which is negative for ZIP8.

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