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Figure 5 | Cancer Cell International

Figure 5

From: ZIP8 expression in human proximal tubule cells, human urothelial cells transformed by Cd+2 and As+3 and in specimens of normal human urothelium and urothelial cancer

Figure 5

Immunoperoxidase staining of ZIP8 in high grade urothelial carcinoma. A &B. Noninvasive urothelial carcinoma showing weak staining of ZIP8 (+). Asterisks (*) indicate stromal tissue which is negative for ZIP8. C. Noninvasive urothelial carcinoma with focal moderate staining of ZIP8 (+). Asterisks (*) indicate stromal tissue which is negative for ZIP8. D. Invasive urothelial carcinoma with negative staining of ZIP8 (−). Few smooth muscle fibers between the invasive tumor nests are weakly positive for ZIP8 (*). E. Invasive urothelial carcinoma with focal weak staining of ZIP8 (+). Asterisks (*) indicate stromal tissue which is negative for ZIP8. F. Invasive urothelial carcinoma with weak staining of ZIP8 (+). A few spindled shaped stromal cells are also weakly positive for ZIP8 (*). G. Anaplastic urothelial carcinoma showing moderate staining for ZIP8 (+). Asterisks (*) indicate stromal tissue which is negative for ZIP8. H. Invasive urothelial carcinoma with moderate to strong staining of ZIP8 (*). A few spindled shaped stromal cells are weakly positive for ZIP8 (*). I. Poorly differentiated urothelial carcinoma with strong staining for ZIP8 (+). Asterisks (*) indicate stromal tissue which is negative for ZIP8.

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Cancer Cell International

ISSN: 1475-2867

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