Paralemmin-1 is over-expressed in estrogen-receptor positive breast cancers

Table 1 Breast cell lines examined for paralemmin-1 mRNA and protein expression

Cell Line	Donor Age	Pathology	ER	Paralemmin-1 Expression
				RNA	Protein (kDa)
MCF-7	69	IDC	Pos	medium	65, 55
T47D	54	IDC	Pos	low	65*
ZR-75-1	47	IDC	Pos	medium	65*, 55
BT-20	74	IDC	Neg¹	low	65, 55
TMX2-28⁴	69	IDC	Neg	high	65, 55
MDA-MB-231	51	Adeno	Neg	low	none
MCF-10A	36	NE	Neg	medium	65
184²	15-66	NE	Neg	low	none
184A1³	15-66	NE	Neg	low	none
184AA2³	15-66	NE	Neg	low	none

¹BT-20 cells express ER mRNA, but do not express ER protein; ²Non-tumorigenic mammary cell line from Dr. Martha Stamfer’s Laboratory ³Derivative of 184 cells; ⁴Derivative of MCF-7 cells IDC: Invasive ductal carcinomas Adeno: Adenocarcinoma; NE: Normal epithelial; Sources:[6–8]; *indicates a faint band.

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