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Table 1 Effect of lycopene (1-5 μM) on cell cycle progression in different human cancer cell lines after 48 hours

From: Effect of lycopene on cell viability and cell cycle progression in human cancer cell lines

Cell Lines

Cell Cyle phases

CT

1 μM

3 μM

5 μM

HT-29

G0/G1

47.40 ± 0.57

61.65 ± 3.61*

55.10 ± 1.41*

59.05 ± 7.42*

S

21.30 ± 4.53

19.70 ± 0.42

19.75 ± 0.49

20.70 ± 0.85

G2/M

18.55 ± 3.61

13.70 ± 1.84

18.90 ± 0.42

12.45 ± 3.18

T84

G0/G1

42.20 ± 0.39

40.31 ± 0.40

41.10 ± 0.71

44.96 ± 2.76*

S

10.93 ± 0.13

11.90 ± 0.60

10.25 ± 1.07

10.60 ± 0.45

G2/M

33.00 ± 0.09

35.03 ± 1.74

33.90 ± 0.88

31.53 ± 0.81*

MCF-7

G0/G1

29.45 ± 2.05

29.15 ± 1.48

32.65 ± 0.49*

33.20 ± 1.13*

S

17.00 ± 4.24

18.05 ± 2.90

16.75 ± 3.18

17.35 ± 0.92

G2/M

36.50 ± 0.71

34.50 ± 0.71

16.90 ± 1.27*

22.40 ± 1.98*

A549

G0/G1

55.64 ± 0.28

57.84 ± 0.77

56.34 ± 0.14

58.82 ± 0.33*

S

14.85 ± 0.05

13.99 ± 0.16

14.32 ± 0.23

13.43 ± 0.45

G2/M

31.01 ± 0.28

29.58 ± 0.73

30.82 ± 0.02

28.86 ± 0.81

DU145

G0/G1

47.73 ± 2.21

48.49 ± 0.81

46.46 ± 4.21

56.14 ± 1.33*

S

13.52 ± 1.12

12.46 ± 0.44

11.47 ± 1.27

9.10 ± 0.76

G2/M

36.76 ± 0.76

36.24 ± 0.35

36.14 ± 1.61

31.20 ± 0.54*

HepG2

G0/G1

28.70 ± 2.40

29.75 ± 0.35

25.20 ± 2.55

28.45 ± 0.78

S

17.80 ± 2.55

16.85 ± 0.21

16.20 ± 1.70

16.20 ± 1.13

G2/M

27.95 ± 1.34

26.82 ± 0.99

25.30 ± 4.53

25.70 ± 1.84

Hela

G0/G1

62.42 ± 0.31

62.48 ± 0.08

63.49 ± 1.33

63.59 ± 2.26

S

10.35 ± 0.28

9.02 ± 0.59

8.19 ± 0.24

7.86 ± 0.33

G2/M

25.87 ± 0.27

26.36 ± 0.28

24.90 ± 0.32

26.19 ± 0.12

Hep2

G0/G1

64.80 ± 0.25

67.02 ± 0.54

66.98 ± 0.00

63.97 ± 0.50

S

6.83 ± 0.05

6.75 ± 0.38

7.31 ± 0.08

7.48 ± 0.72

G2/M

28.56 ± 0.20

26.45 ± 0.66

26.98 ± 1.28

28.99 ± 0.16

  1. Results are expressed as the percentage of total cells. Data represent mean ± SD values of triplicate experiments. Tukey–Kramer Multiple Comparison test; *p < 0.05; **p < 0.01