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Table 2 Effect of lycopene (1-5 μM) on cell cycle progression in different human cancer cell lines after 96 hours

From: Effect of lycopene on cell viability and cell cycle progression in human cancer cell lines

Cell Lines Cell Cycle phase CT 1 μM 3 μM 5 μM
HT-29 G0/G1 77.14 ± 0.02 84.37 ±0.10* 40.29 ± 5.40** 46.07 ± 0.68**
S 8.31 ± 0.45 4.40 ± 1.06 19.59 ± 4.02* 9.30 ± 0.47
G2/M 13.41 ± 0.70 10.17 ± 0.32* 34.72 ± 0.86** 40.03 ± 0.38**
T84 G0/G1 28.14 ± 0.01 41.84 ± 1.53** 32.97 ± 0.28** 36.06 ± 0.06**
S 17.86 ± 1.03 17.52 ± 0.05 18.85 ± 0.20 19.39 ± 3.93
G2/M 43.67 ± 0.01 38.51 ± 1.48* 45.64 ± 0.51 50.23 ± 0.01*
MCF-7 G0/G1 17.10 ± 1.56 22.45 ± 0.78* 19.30 ± 0.99* 20.20 ± 1.13*
S 26.25 ± 0.35 26.95 ± 0.07 24.15 ± 1.20 22.95 ± 1.48
G2/M 40.50 ± 0.71 33.85 ± 1.20* 30.20 ± 0.28* 24.95 ± 0.07**
A549 G0/G1 65.82 ± 2.62 63.48 ± 4.47 66.62 ± 3.59 61.54 ± 1.14
S 14.10 ± 3.29 13.61 ± 2.64 11.55 ± 2.67 14.90 ± 0.36
G2/M 21.31 ± 0.83 24.56 ± 2.21* 23.40 ± 1.41* 25.18 ± 0.73*
DU145 G0/G1 56.24 ± 7.90 46.12 ±15.97 25.99 ± 7.43** 16.76 ± 1.61**
S 12.19 ± 3.79 16.36 ± 3.25 8.02 ± 2.14 8.57 ± 1.70
G2/M 29.89 ± 3.99 31.26 ± 5.85 56.97 ± 6.24** 55.93 ± 5.53**
HepG2 G0/G1 59.68 ± 0.09 47.17 ± 4.18* 23.23 ± 0.59** 19.91 ± 5.82**
S 12.33 ± 0.86 10.68 ± 2.74 7.04 ± 0.52* 7.91 ± 2.71
G2/M 26.39 ± 0.41 36.63 ± 7.25* 57.84 ± 1.53** 59.49 ±7.52**
Hela G0/G1 62.42 ± 0.01 62.48 ± 0.08 63.49 ± 1.33 63.59 ± 2.26
S 10.35 ± 0.18 9.02 ± 0.59 8.19 ± 0.24 7.86 ± 0.33
G2/M 25.87 ± 0.27 26.36 ± 0.28 24.90 ± 0.32 26.19 ± 0.12
Hep-2 G0/G1 62.78 ± 4.35 69.50 ± 4.65 63.39 ± 0.07 61.83 ± 7.97
S 18.73 ± 2.57 12.72 ± 3.64 16.79 ± 0.73 17.77 ± 5.70
G2/M 20.66 ± 1.48 18.65 ± 1.92 20.31 ± 0.72 20.53 ± 2.57
  1. Results are expressed as the percentage of total cells. Data represent mean ± SD values of triplicate experiments. Tukey–Kramer Multiple Comparison test; *p < 0.05; **p < 0.01