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Table 1 Summary of marker expression determined by RT-PCR

From: Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall

Stem cell markers   Proliferation, angliogenic, migration markers, growth factors, adhesion
SOX2 ++++++ Ki67 +++++
DACH1 + VEGF +++
CD133 ++++ HIF1 +
Nestin +++ CXCR4 ++
Nucleostemin ++++ SDF1 +
   IGF1R ++
   NCAM +++
Glial Cells   PAX6 ++++
GFAP ++   
   Ephrins receptors and ligands (cell repulsion, adhesion, migration)
Neuronal   EphB1 Receptor n/a
DCX + EphB2 Receptors ++++++
MSI + EphB3 Receptors +++++
MAP2 + EFNB1\ +
Neural Specific Endolase ++++ EFNB2 ++
Beta-3Tubulin III + EFNB3 +
   MMPs, Peptidases ++
   MMP2 +++
Tumor Suppressors/Oncogenes   TIMP1  
p53 + MMP9 +++
PTEN + MMP13 ++++
Bmi-1 ++ MMP14 +
CAV-1 ++ Cathepsin B +
CAV-2 + Cathepsin L +++
c-Myc +++   
   Controls  
Proteoglycans   GAPDH +++
Mucin9 ++ Beta-Actin ++
Mucin18 + H2O  
Mucin24 ++++   
Notch-Family    
Notch1 +   
Notch2 +++   
Notch3 +   
Notch4 ++   
  1. Low-level expression is designated as “+” while medium level expression is designated as “++” to “+++++” and the highest level is designated as “++++++”.