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Table 3 Effect of RSVL treatment on the cellular uptake of DOX in MCF-7 cells

From: Modulation of doxorubicin cytotoxicity by resveratrol in a human breast cancer cell line

Treatment

DOX Concentration (μg/106 x cells)

 

Alone

Simultaneously with RSVL

RSVL 24 h before

DOX (0.5 μg/ml)

0.041 ± 0.008

0.062 a ± 0.011

0.023 ± 0.001

DOX (0.25 μg/ml)

0.027 ± 0.004

0.031 ± 0.005

0.024 ± 0.001

DOX (0.125 μg/ml)

0.022 ± 0.004

0.021 ± 0.004

0.013 ± 0.002

  1. Each data is the mean ± S.E.M of two experiments each one in duplicate. aSignificantly different from DOX at P-value < 0.05.