Figure 5
From: Lycorine induces cell-cycle arrest in the G0/G1 phase in K562 cells via HDAC inhibition
Effects of lycorine on expression of p21, p53 and pRB, and phosphorylation of pRB in K562 cells. Lanes 1, 2, 3, and 4 represent K562 cells treated with 0, 1.25, 2.5, and 5.0 μM lycorine, respectively. α-tubulin was used for normalization and verification of protein loading in Western blot analysis. Results are presented as mean ± S.D. (n = 3, three independent experiments).