Figure 1
17-AAG and GA induces c-FLIP L down-regulation in NSCLC cells. (A) and (B), Calu-1, H157, A549 and H460 cell lines were treated with either 17-AAG or GA at the indicated concentration for 48 h. (C), Calu-1 and H157 cells were treated with 1.0 μM 17-AAG or 4.0 μM GA for the indicated time. The cells were subjected to preparation of whole-cell protein lysates and c-FLIPL proteins were detected by Western blot analysis.