Analysis of volatile organic compounds released from human lung cancer cells and from the urine of tumor-bearing mice

Table 6 Summary of VOCs detected in headspace of mice urine

Compound	CAS	Retention time (min)	control mice		tumor-bearing mice		p-value (ANOVA)	Ratio (tumor/control)
Compound	CAS	Retention time (min)	Average (μM)	SD	Average (μM)	SD
2-Butanone	78-93-3	10.5	8.808	1.154	13.226	1.297	0.02	1.5
2-Pentanone	107-87-9	14.7	2.180	0.209	2.599	0.142	0.08	1.2
2-Hexanone	591-78-6	19.8	0.085	0.016	0.134	0.010	0.02	1.6
2-Methylpyrazine	109-08-0	27.0	0.201	0.029	0.455	0.109	0.03	2.3
Dimethyl Succinate	106-65-0	36.3	0.237	0.017	0.334	0.038	0.03	1.4
Acetophenone	98-86-2	38.1	2.310	0.499	3.912	0.399	0.02	1.7
Phenol	108-95-2	45.6	1.824	0.207	2.722	0.213	0.01	1.5

The VOC concentrations are shown with standard deviations. The p-values were calculated by ANOVA. The ratio is a comparison of average concentrations of tumor-bearing mice and control mice

ISSN: 1475-2867