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Table 1 Baseline characteristics of the 18 eligible studies for the analysis of IL-8-251 A > T polymorphism

From: Positive association between Interleukin-8 -251A > T polymorphism and susceptibility to gastric carcinogenesis: a meta-analysis

Studies Year Country Ethnicity Source of controls Number of controls Number of case Genotyping method HWE
Burada F 2012 Romanian Caucasian HB 242 105 Real-time PCR 0.386
Canedo P 2007 Portugal Caucasian PB 693 401 Taqman 0.460
Crusius JB 2008 European Caucasian HB 1139 428 Real-time PCR 0.706
Kamangar F 2006 Finland Caucasian PB 207 112 Taqman 0.055
Kang JM 2009 Korea Asian HB 322 645 RFLP 0.226
Lee WP 2005 Taiwan Asian HB 308 461 RFLP 0.143
Liu J 2009 China Asian HB 137 417 Taqman 0.145
Lu W 2005 China Asian PB 300 250 DHPLC 0.516
Ohyauchi M 2005 Japan Asian PB 346 212 Direct sequence analysis 0.549
Savage SA 2004 Poland Caucasian PB 429 88 SBE 0.885
Savage SA 2006 Poland Caucasian PB 428 287 Taqman or MGB Eclipse 0.391
Shirai K 2005 Japan Asians HB 468 181 RFLP 0.830
Song B 2010 China Asian HB 190 208 RFLP 0.389
Taguchi A 2005 Japan Asian HB 252 611 RFLP 0.994
Vinagre RM 2011 Brazil Mixed HB 103 102 RFLP 0.151
Ye BD 2009 Korea Asian HB 206 399 RFLP 0.553
Zeng ZR 2005 China Asian PB 196 206 PCR-RDB 0.022
Zhang LW 2010 China Asian PB 504 519 PCR-RFLP 0.754
  1. PB, population-based controls; HB, hospital-based controls. HWE, Hardy–Weinberg equilibrium. PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; SBE, single base extension; PCR-RDB, polymerase chain reaction- reverse dot blot.
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