Figure 4
From: HOXB1 restored expression promotes apoptosis and differentiation in the HL60 leukemic cell line
Surface markers and morphological analysis in LXSN- and HOXB1-transduced HL60. CD11b positive cells at day 0, 3 and 7 of ATRA (10-7 M) treatment (a). Morphological analysis (b) and representative pictures (c) of ATRA-treated granulocytic-like cells. CD11b/CD14 double positive cells at day 0, 3 and 11 of VitD3 (10-8 M) treatment (d). Morphological analysis (e) and representative pictures (f) of VitD3-treated monocytic-like cells. Cells were detected by the Giemsa-McGrünwald colorimetric method. Arrowheads indicate mature cells, long arrows blasts and double arrows intermediate cells.