Figure 2

Fungal taxol and baccatin III exhibit concentration- and time-dependent apoptosis in JR4-Jurkat cells. Cells (0.25 × 106) were treated with fungal taxol (A) or baccatin III (B) at indicated concentrations for 48 h. A time-course experiment of fungal taxol- and baccatin III-induced apoptosis (C). Other details are as described in legend to Figure 1. The percentage of apoptotic cells (sub G1 peak) was calculated on the basis of respective histograms.