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Figure 4 | Cancer Cell International

Figure 4

From: Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani

Figure 4

Effect of fungal taxol and baccatin III on apoptosis. Caspase-8-deficient Jurkat (A and B) and anti-apoptotic protein Bcl2-overexpressing J16 Jurkat cells (C) (0.25 × 106) were treated with fungal taxol or baccatin III at indicated concentrations for 48 h or indicated time periods and assayed with PI staining followed by flow cytometry. The percentage of apoptotic cells (sub G1 peak) was quantified and plotted. (D) Relative levels of fungal taxol- and baccatin III- induced apoptosis in the three cell lines after 48 h.

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