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Figure 2 | Cancer Cell International

Figure 2

From: CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin

Figure 2

Effect of CpG-ODN and/or 5-FU treatment on the cell morphology of HepG2 cells. A: Morphologic changes of HepG2 cells treated with the indicated concentration of CpG-ODN and 5-FU alone or together for 48 h, compared with untreated cells (medium) (100X). B: HepG2 cells treated with the indicated concentration of CpG-ODN and 5-FU alone or together for 48 h, then stained with Hoechst 33258(400 X). Condensed and fragmented nuclei in cells were marked by arrow heads. In this figure, 5-FU, CpG(2) and CpG(4) represent that the concentration of 5-FU, CpG-ODN and CpG-ODN is 7.5 μg/ml, 2 μM, 4 μM, respectively.

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