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Table 2 The association between FPGS rs1544105 genotypes and patient characteristics (N = 164)

From: FPGS rs1544105 polymorphism is associated with treatment outcome in pediatric B-cell precursor acute lymphoblastic leukemia

Characteristics FPGS SNP rs1544105 p-value*
CC CT + TT
genotype genotype
Gender    1.000
Male 9 (62.3) 95 (63.3)
Female 5 (35.7) 55 (36.7)
Age (years)    0.336
<1 0 0
1-9 13 (92.9) 123 (82.0)
≥10 1 (7.1) 27 (18.0)
Treatment group    0.797
SR 4 (28.6) 58 (38.7)
MR 8 (57.1) 73 (48.7)
HR 2 (1.3) 19 (12.6)
WBC (109/L)    0.710
<50 11 (78.6) 125 (83.3)
≥50 3 (21.4) 25 (16.7)
TEL-AML1    0.770
Positive 3 (21.4) 38 (25.3)
Negative 11 (78.6) 112 (74.7)
E2A-PBX1    1.000
Positive 1 (7.1) 15 (10.0)
Negative 13 (92.9) 135 (90.0)
BCR-ABL    0.141
Positive 2 (14.3) 6 (4.0)
Negative 12 (85.7) 144 (96.0)
MLL-AF4    1.000
Positive 0 1 (0.6)
Negative 14 (100.0) 149 (99.4)
Prednisone response    0.164
Good 1 (7.1) 1 (0.6)
Poor 13 (92.9) 149 (99.4)
CNS involvement    1.000
Absent 14 (100.0) 148 (98.7)
Present 0 2 (1.3)
  1. *Data were calculated by χ2 test. WBC, white blood cell count; SR, standard-risk; MR, medium-risk; HR, high-risk; CNS, central nervous system.
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