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Figure 10 | Cancer Cell International

Figure 10

From: Targeted inhibition of heat shock protein 90 disrupts multiple oncogenic signaling pathways, thus inducing cell cycle arrest and programmed cell death in human urinary bladder cancer cell lines

Figure 10

Hsp90 inhibition eliminates the “hallmark traits” of cancer. The data presented here clearly demonstrate that the geldanamycin-induced inhibition of Hsp90 results in the combinatorial and multi-step impairment of critical oncogenic pathways likely implicated in the “hallmark traits” of bladder cancer initiation and progression.

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Cancer Cell International

ISSN: 1475-2867

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