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Figure 3 | Cancer Cell International

Figure 3

From: Targeted inhibition of heat shock protein 90 disrupts multiple oncogenic signaling pathways, thus inducing cell cycle arrest and programmed cell death in human urinary bladder cancer cell lines

Figure 3

Caspase-dependent activation of programmed cell death. Expression and proteolytic processing patterns of apoptosis-related critical proteins in response to 24 hours of geldanamycin treatment in RT4 and T24 bladder cancer cells. Western blottings of members of the caspase signaling cascade (caspase-8, -9 and −3) and the caspase repertoire substrates PARP and Lamin A/C are shown. Actin has been used as protein of reference. Data are obtained from three different experimental trials, one of which is presented here.

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Cancer Cell International

ISSN: 1475-2867

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