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Figure 4 | Cancer Cell International

Figure 4

From: Targeted inhibition of heat shock protein 90 disrupts multiple oncogenic signaling pathways, thus inducing cell cycle arrest and programmed cell death in human urinary bladder cancer cell lines

Figure 4

Autophagy-mediated programmed cell death. Characteristic images of RT4 and T24 bladder cancer cell activation of autophagy in response to 1 μM of geldanamycin treatment (scale bars: 10 μm). Cells were stained with Lysotracker Red that specifically recognizes active lysosomes (white arrows), therefore allowing the detection of an autophagic cell death program. Images were taken under a Nikon EZ-C1 confocal microscope. All cell staining experiments were conducted three times, while a representative image collection is shown here.

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Cancer Cell International

ISSN: 1475-2867

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