Skip to main content

Table 1 Antitumor activities of the isolated compounds on the proliferation of different cell lines

From: Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on human cancer cells

Compound

Inhibitory Rate for Different Cell Lines (%, mean ± SD)a

 

MGC-803

PC3

A549

MCF-7

NIH3T3

β-sitosterol (1)

23.5 ± 2.1

16.5 ± 2.3

12.6 ± 3.1

18.9 ± 1.7

5.6 ± 2.4

α-Amyrin (2)

23.5 ± 5.4

17.8 ± 4.9

7.8 ± 1.5

10.4 ± 1.8

7.6 ± 4.5

Daucosterol (3)

12.3 ± 4.1

9.8 ± 3.6

4.5 ± 1.8

7.2 ± 5.2

4.3 ± 2.3

Quercetin (4)

17.2 ± 1.7

22.7 ± 1.4

16.9 ± 2.4

42.2 ± 1.6

4.2 ± 2.5

(+)-Catechin (5)

52.1 ± 5.7

49.6 ± 2.3

45.3 ± 3.2

37.6 ± 3.9

28.9 ± 4.3

(−)-Epicatchin (6)

45.5 ± 4.1

50.6 ± 1.6

47.1 ± 1.1

43.2 ± 3.6

22.5± 3.8

Kampferol (7)

58.2 ± 3.0

46.1 ± 5.9

42.0 ± 2.2

39.2 ± 6.8

11.1 ± 6.7

3-Oxours-12-en-28-oic acid (8)

45.2 ± 2.0

42.5 ± 1.4

35.9 ± 0.8

37.2 ± 1.5

23.6 ± 1.3

Ursolic acid (9)

52.1 ± 2.2

55.6 ± 2.4

37.6 ± 1.7

47.8 ± 1.2

21.7 ± 4.9

Betulonic acid (10)

56.1 ± 2.6

63.4 ± 4.2

35.2 ± 2.4

51.2 ± 4.4

22.1 ± 6.2

Gallic acid (11)

55.7± 1. 9

40.2 ± 4.2

46.3 ± 3.6

33.1 ± 1.4

13.6 ± 2.2

Betulinic acid (13)

36.9 ± 1.6

23.6 ± 3.4

33.5 ± 2.3

41.6 ± 3.7

23.4 ± 2.9

ADM

92.1 ± 1.3

93.4 ± 2.6

96.2 ± 0.8

91.1 ± 2.2

99.4 ± 0.4

  1. Note: a Inhibitory percentage of cells treated with each compound 20 μ mol/L for 72 h and SD = standard deviation.