From: Expression of MACC1 and c-Met in human gastric cancer and its clinical significance
Clinicopathological features | No. of cases | MACC1 | c-Met | ||||
---|---|---|---|---|---|---|---|
(+) | (-) | P | (+) | (-) | P | ||
Age(years) | |||||||
<55 | 41 | 24 | 17 | 0.643 | 25 | 16 | 0.760 |
≥55 | 57 | 36 | 21 | 33 | 24 | ||
Gender | |||||||
Male | 69 | 42 | 27 | 0.911 | 41 | 28 | 0.941 |
Female | 29 | 18 | 11 | 17 | 12 | ||
Maximal tumor size(cm) | |||||||
<5 | 54 | 34 | 20 | 0.696 | 35 | 19 | 0.209 |
≥5 | 44 | 26 | 18 | 23 | 21 | ||
Tumor location | |||||||
Cardia, fundic, body | 43 | 30 | 13 | 0.125 | 29 | 14 | 0.141 |
Antral | 55 | 30 | 25 | 29 | 26 | ||
Histology | |||||||
Well differentiated | 39 | 20 | 19 | 0.101 | 20 | 19 | 0.196 |
Poorly differentiated | 59 | 40 | 19 | 38 | 21 | ||
Lymphnode metastasis | |||||||
Yes | 72 | 51 | 21 | 0.001* | 47 | 25 | 0.041* |
No | 26 | 9 | 17 | 11 | 15 | ||
Peritoneal dissemination | |||||||
Yes | 26 | 21 | 5 | 0.017* | 20 | 6 | 0.032* |
No | 72 | 39 | 33 | 38 | 34 | ||
Hepatic metastasis | |||||||
Yes | 18 | 15 | 3 | 0.033* | 15 | 3 | 0.021* |
No | 80 | 45 | 35 | 43 | 37 | ||
TNM stage | |||||||
I,II | 43 | 23 | 20 | 0.165 | 22 | 21 | 0.153 |
III,IV | 55 | 37 | 18 | 36 | 19 | ||
MACC1 | |||||||
(+) | 43 | 17 | 0.002* | ||||
(-) | 15 | 23 | |||||
Odds ratio | 3.878 |