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Table 1 H 2 O 2 leukemic primitive cell clonogenic capacity

From: Hydrogen peroxide (H2O2) induces leukemic but not normal hematopoietic cell death in a dose-dependent manner

  Unstimulated 5 μM H2O2
BM 68 ± 2 86 ± 7*
UCB 45 ± 4 12 ± 2*
HL-60 310 ± 4 0*
  1. A methylcellulose clonal assay was used to quantify clonogenic capacity of primitive cells obtained from BM, UCB and HL-60 lineage. Clonogenic capacity of BM was increased, showing that H2O2 induced the improvement of the capability of these cells to generate their progeny. UCB colonies decreased around 70% while HL-60 stimulated with H2O2 was not able to generate clones. The data are expressed as the mean ± SEM of 4 experiments. *P< 0.05, ANOVA.