Widely expressed Mirk/Dyrk1B in the human cancer cells is positively correlated with activated ERK1/2. (A), preotein expressions of Mirk (69 and 71 Kda), ERK1/2 and P-ERK1/2 (42/44 kDa) in ovarian cancer and NSCLC cells were measured by western blot analyses, with equal loading and transfer shown by repeat probing with β-actin (42 kDa). (B), the correlation between the protein expressions of Mirk and P-ERK1/2 was analyzed by simple regression. Units, intensity/mm2. NSCLC, non-small cell lung cancer; ERK, extracellular signal-regulated kinase.