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Table 2 Tumorigenicity and metastasis of the two cell lines following orthotopic transplantation in nude mice

From: Establishment and characterization of clear cell renal cell carcinoma cell lines with different metastatic potential from Chinese patients

Round No.

Tumor source

Incidence of tumorigenicity (a/b) †

Enlarged lymph nodes near the ventral aorta

Pulmonary metastasis (a/b) †

Hemorrhagic ascites (a/b) †

Cachexy (a/b) †

MRCC

      

1

Primary

5/5

No

0/5

0/5

0/5

2

Primary

5/5

Yes

4/5

4/5

2/5

3

Metastasis

5/5

Yes

4/5

4/5

3/5

4

Metastasis

5/5

Yes

4/5

2/5

3/5

5

Metastasis

5/5

Yes

5/5

3/5

5/5

6

Metastasis

5/5

Yes

5/5

3/5

5/5

NRCC

      

1

Primary

4/5

No

0/5

0/5

0/5

2

Primary

5/5

No

0/5

0/5

0/5

3

Primary

5/5

No

0/5

0/5

0/5

  1. † a, the number of mice with the event of interest (tumorigenicity, metastasis, hemorrhagic ascites or cachexy);
  2. b, total number of mice orthotopically transplanted with the minced tumor masses.