Figure 3From: Arsenic trioxide inhibits the proliferation of myeloma cell line through notch signaling pathwayATO decreased the level of Notch signal expression of RPMI8226 cells, (A) myeloma cell was treated with different concentration ATO for 48 h, the expression of Notch1 and Jagged2 was obviously decreased. (B) with 5 μM ATO, myeloma cell was treated for 24, 48, and 72 hours, the level of Notch1 ,jagged2 expression were significantly reduced.Back to article page