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Figure 4 | Cancer Cell International

Figure 4

From: The novel mTOR inhibitor CCI-779 (temsirolimus) induces antiproliferative effects through inhibition of mTOR in Bel-7402 liver cancer cells

Figure 4

Activation of mTOR and its downstream molecules is inhibited by CCI-779 in Bel-7402 cells. Expression of mTOR, p70S6K, S6, and 4EBP1 and phosphorylation status of mTOR (Ser2448), p70S6K (Thr389), S6 (Ser240/244), and 4EBP1(Ser37/46) were examined by western blot 48 h after the addition of CCI-779. β-actin served as gel control.

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Cancer Cell International

ISSN: 1475-2867

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