Figure 6
From: Notch1 signaling is involved in regulating Foxp3 expression in T-ALL
Jurkat cells cycle after DAPT treatment. The effect of DAPT on cell cycle was determined by flow cytometric analysis. Jurkat cells were treated with increasing concentrations of DAPT (1, 5, 10, 20 μM) for 48 hours. The percentage of Jurkat cells in the sub-G0/G1 phase increased significantly while in S and G2/M phase decreased compared to the cells alone and DMSO control (P < 0.05).